Profile details

• Gliadin Antibodies (IgG) (deamidated)
• HLA Tissue Typing Coeliac Disease – DQ2/DQ8
• Immunoglobulin A
• Tissue Transglutaminase IgA (Coeliac)
• Gliadin Antibodies (IgG) (deamidated)
• Immunoglobulin A
• Tissue Transglutaminase IgA
• HLA Tissue Typing DQ2/DQ8

Code

GSA2

Sample Reqs

AB

Turnaround

10 days

Special instructions

If IgA deficiency is identified, a reflex deamidated Gliadin IgG will be carried out to determine whether the patient is likely to have coeliac disease. Coeliac pathway:

1. Initial TTG IgA samples are received and tested
2. If TTG IgA is LOW <0.2 U/ml reflex testing for Total IgA will be undertaken
3. If Total IgA is LOW <0.1 g/L then reflex testing for deamidated Gliadin IgG test will be undertaken
4. If TTG IgA is HIGH >/= 10 U/ml then reflex testing for Endomysial IgA will be undertaken as a confirmatory test for first time positive samples.