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Gluten Sensitivity Profile

Profile details

  • Gluten Single IgE Allergen
  • Gliadin Antibodies (IgG) (deamidated)
  • HLA Tissue Typing Coeliac Disease – DQ2/DQ8
  • Immunoglobulin A
  • Tissue Transglutaminase IgA (Coeliac)

Code

GLUT

Sample Reqs

ABB

Turnaround

10 days

Special instructions

If IgA deficiency is identified, a reflex deamidated Gliadin IgG will be carried out to determine whether the patient is likely to have coeliac disease. Coeliac pathway:

  1. Initial TTG IgA samples are received and tested
  2. If TTG IgA is LOW <0.2 U/ml reflex testing for Total IgA will be undertaken
  3. If Total IgA is LOW <0.1 g/L then reflex testing for deamidated Gliadin IgG test will be undertaken
  4. If TTG IgA is HIGH >/= 10 U/ml then reflex testing for Endomysial IgA will be undertaken as a confirmatory test for first time positive samples.


Sample type guide

A

Lavender Vacutainer, EDTA anticoagulant, 4ml/6ml (6ml EDTA tubes are used for specific PCR assays)

B

Gold Vacutainer, SST/Gel anticoagulant, 5ml


Related specialties

Updated Saturday, 14 December 2024