Stockholm3 test for Prostate Cancer
Stockholm3 is a blood test that helps to predict risk of clinically significant prostate cancer in men aged 45–74 years with a PSA level of at least 1.5 ng/ml and no previous diagnosis of prostate cancer.
Stockholm3 combines genetic markers, proteins and clinical data in an algorithm to help identify clinically significant prostate cancer. It allows for screening in primary or secondary care settings and is equivalent across diverse ethnicities.
Stockholm3 has been prospectively validated in more than 90,000 men with results published in more than 30 peer reviewed articles. It provides clear, interpretable results (High risk, Normal risk, Low risk) and treatment recommendations.
Key characteristics
- Increased early detection – increased sensitivity
- Increased specificity reduces over testing, unnecessary biopsies by 50% and treatment
- Higher accuracy compared to PSA, PSAD and prostate cancer risk calculator
- PSA testing cannot distinguish between aggressive and benign tumours
- Validated in combination with MRI and in multiple ethnicities
- Shown to detect clinically significant prostate cancers in PSA levels of 1.5–2.9 ng/ml
- Reduces healthcare costs
Stockholm3 in a typical diagnostic patient pathway
|
Gender |
Male |
|
Intended age |
45–74 years, not had prostate cancer, PSA > 1.5 ng/ml |
|
Clinical data |
Age, family history of prostate cancer, previous biopsies, use of 5-alpha reductase inhibitors (Avodart [Dutasteride] or Proscar [Finasteride]. |
|
Test code |
STK3 |
|
Sample type |
A A must be received by TDL within 24 hours of sample taking |
|
Turnaround time |
2 weeks |
A Stockholm3 risk score of >11 is considered to be an indicator of clinically significant prostate cancer risk and referral for further investigations is recommended.
To order the Stockholm3 test, take and send 2 x EDTA tubes, which must be received by the laboratory within 24 hours of sample taking.
TDL will provide sample taking kits/request forms – to order, or for further information, please contact stockholm3@tdlpathology.com. These packs do not include a reply-paid envelope. The timing for receipt of samples is important – please do not post samples to TDL.