Tests

See the Lab Guide’s Explanation of Sample Requirements for key to sample codes.

 

TestCodeSample ReqsTurnaroundSpecial
Instructions
Chlamydia trachomatis in semen (PCR) UPCR Semen 3 days  
Infection screen 7 x STD in semen (PCR) PP12 Semen 3 days  
Semen Analysis, Comprehensive SPER Semen 2 days* 1
Semen Analysis, Vasectomy Reversal SPER Semen 2 days* 1
Semen Analysis, Post-Vasectomy** PVAS Semen 2 days 1
Semen Culture SPCU Semen 2-3 days  
Semen Fructose SPCF Semen 2 days  
Sperm Antibodies (Serum) ASAB B 5 days  
Sperm Antibodies /MAR Test (Semen)*** ASPA Semen 1 day 1
Sperm Aneuploidy SPPL Semen 4 weeks 1
Sperm DNA Fragmentation (SCSA) SEXT Semen 2-3 weeks 1
Sperm Morphology (Kruger strict criteria) MRPH Semen 2 days 1
Oxidative Stress in Semen (ROS) SROS Semen 1 day 1
Retrograde Ejaculation RTRO Contact Lab 2 days 1
Semen Leucocytes PMNS Semen 2 days 1

 

* If required, comprehensive semen analysis can be reported within 4 hrs, with morphology to follow.

 

** The UK guidelines state that clearance may only be given and contraception dispensed with, when there is no evidence of presence of sperm in a single ejaculate when recommendations (see below) are met. It is rare that a ‘diagnosis’ is made without confirmation, therefore patients/clinicians should be able to freely request a second confirmatory sample.


Recommendations


Recommendations, as given by the Association of Biomedical Andrologists, the British Andrology Society and the British Association of Urological Surgeons 2016, are as follows:

  • Analysis of post vasectomy semen samples should not occur until 12 weeks post-surgery and after a minimum of 20 ejaculates
  • Semen samples must be analysed within 4hrs of production, and in cases where sperm is found a repeat analysis must be performed within 1hr of production
  • Semen should be produced in screened specimen containers provided by TDL Andrology
  • Sexual abstinence should be between 2 and 7 days

***  Sperm antibodies in semen are measured as part of the routine semen analysis.

 

 

Profiles

See the Lab Guide's Explanation of Sample Requirements for key to sample codes.

 

Male Infertility Profile 1
TAT 4 hours
  • FSH
  • LH
  • Testosterone
  • Free Androgen Index
  • Prolactin
  • SHBG





MIPR
B
Male Infertility Profile 2
TAT 10 to 15 days
  • FSH
  • Testosterone
  • Inhibin B
  • SHBG and FAI
  • LH
  • Prolactin
  • Chromosome Analysis
  • Y Chromosome Microdeletion (AZFa, b and c)
  • Cystic Fibrosis (33 mutations)
Semen analysis will be invoiced as an extra test. Please request if required.
MIP2 9
A
A
B
B
B
H
Male Genetic
Reproductive Profile
TAT 10 to 15 days
  • Chromosome Analysis
  • Y Chromosome Microdeletion
  • Cystic Fibrosis Carrier Screen (33 mutations





GRP 9
A
A
H
CBAVD Profile (Azoospermia)
TAT 10 to 15 days
  • Chromosome Analysis
  • Y Chromosome Microdeletion
  • Cystic Fibrosis Carrier Screen (33 mutations)
  • PolyT (5T, 7T, 9T)








CAVD 9
A
A
H
Male Recurrent
Miscarriage Profile
  • Sperm DNA Fragmentation
  • Sperm Aneuploidy
  • Infection Screen (DL12)








MRMP
Semen
Fit for Fertility Male
  • FBC/ESR
  • Biochemistry (as for DL2)
  • Zinc
  • Red Cell Glutathione
  • Red Cell Folate
  • Vitamin D
  • Sexual Health Screen (Urine)
    Chlamydia, Gonorrhoea, Mycoplasma genitalium, Ureaplasma genitalium, Trichomonas vaginalis, Gardnerella vaginalis, Herpes Simplex I/II
Comprehensive Semen
Analysis can be requested
with this profile as an
additional test.
TAT 8 days
FFFM
A
A
A
A
B
B
H
G
FCRU

 

By Special Arrangement

Sperm swim test
Sperm preparation for overnight survival
Sperm motility and vitality testing for epididymal toxicity
Sperm retrieval procedures (biopsy, PESA, MESA)

Sperm cryopreservation and storage
(undertaken by Anrdrology Solutions – HFEA and EUTD licensed)

All men who store sperm must be screened for HIV 1&2, Hepatitis B, Hepatitis C and HTLV. Under HFEA regulations, sperm can be stored for an initial period of 10 years with formal consent. All patients are offered counselling prior to sperm cryopreservation.


These arrangements, and details for other specialist semen tests, are available on request. Please contact TDL Andrology on 020 7025 7940 or email andrology@tdlpathology.com for further information.